Paclitaxel:
       Paclitaxel  treats a numerous  types of cancer including ovarian cancer, breast cancer, non- small cell lung cancer, Bladder cancer, Sarcoma, Uterine cancer,head and neck cancer, pancreatic cancer, Aggressive Non-Hodgkin lymphoma,Basal cell and squamous cell skin cancer,Cervical cancer, Melanoma,Penile cancer,Testicular cancer,Thymoma, and Uterine cancer. This medicine interferes dynamic restructuring in the break down of microtubules during regular interphase/mitosis processes.  It also creates bundles of microtubules abnormal. People with advanced breast cancer after the failure of anthracyclic chemotherapy are recommended to take Paclitaxel. It is also used in the avoidance of restenosis by acting as an anti proliferate driving force of coronary and stents. It controls the development of neointima within stents. Dissolving with Cremophor EL may cause hypersensitivity infusion reactions.

Side effects caused by Paclitaxel:
fever, chills.
sores in your mouth and throat;.
wheezing.
burning pain in your hands or feet.
swelling or  severe irritation where the injection was given.
pale or purple or red pinpoint spots or bleeding under skin.
feeling light-headed or short of breath.
rapid heart rate.
diarrhea.
constipation.
weakness.
slow heart rate.
seizure.
chest pain.
 dry cough.
jaundice.
vomiting.
joint or muscle pain.
darkening of your skin or nails.
hair loss.
Hand food syndrome.
Female infertility by ovarian damage.
loss of appetite.

Warning Signs while taking Paclitaxel:
       It is advised that frequent blood tests should be taken to avoid risk of bone marrow suppression and serious infection while you are using paclitaxel. Paclitaxel cannot be interchanged or substituted with other forms of same products. It is also instructed that people with allergies to medicines or foods, bacterial or viral infection, or HIV infection are to be consulted with doctor. Persons with heart problems, kidney problems, blood problems, patients under radiation therapy better to take the medicine under the doctor’s prescription. 

Dosage:
       Untreated ovary cancer patients are given 175 mg/m2 or 135 mg/m2 over 3 hours for a period of 3 weeks. Persons with advanced HIV disease reduce the dosage of dexamethasone to 10 mg. Paclitaxel is only continued if the neutrophil count is at least 1000 cells/mm3.